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Allele : Crbn<tm1.1Jjh> cereblon; targeted mutation 1.1, Joseph Higgins

Primary Identifier  MGI:5302187 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Crbn
Transmission  Germline Strain of Origin  B6(Cg)-Tyr<c-2J>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector containing a FRT site flanked PGK-Neo selection cassette and a loxP site was utilized in the construction of this mutant. This selection cassette was inserted 227 bp upstream of exon 3 of the targeted gene, and another loxP site was inserted 225 bp downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exons 3 and 4 floxed.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

10 Publication categories