Primary Identifier | MGI:5301655 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Wwc1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 4. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 5. Cre-mediated recombination removed the exon 4, exon 5, and the neo cassette. Western blot analysis confirmed the absence of protein expression in the brain. |