Primary Identifier | MGI:5302542 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence | Gene | Mecp2 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed neo cassette was inserted upstream of a modified exon in which nucleotide substitution (A to C) results in the amino acid substitution of alanine for serine at position 421 (S421A). Cre-mediated recombination removed the neo cassette. |