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Allele : Nkx2-2<tm3Suss> NK2 homeobox 2; targeted mutation 3, Lori Sussel
Primary Identifier  MGI:5302422 Allele Type  Targeted
Attribute String  Null/knockout, Reporter, RMCE-ready Gene  Nkx2-2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Recombination mediated cassette exchange (RMCE) into Nkx2-2tm1Suss inserted a full length lacZ gene with a nuclear localization signal in place of the existing cassette. Exons 1 and 2 were deleted in the original allele. LacZ expression recapitulates endogenous gene expression.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Nkx2.2<LacZ>,
  • Nkx2.2<LacZ>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories





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