| Primary Identifier | MGI:5305498 | Allele Type | Targeted |
| Gene | Foxo1 | Transmission | Germline |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 2 was replaced with a floxed neo cassette and a modified exon 2 with nucleotide substitutions that result in the amino acid substitutions of glutamine for lysine at positions 219, 242, 245, 259, 262, 271, 291 (K219Q, K242Q, K245Q, K259Q, K262Q, K271Q, and K291Q). These mutations produce a constitutively acetylated allele. Cre-mediated recombination removed the neo cassette. |
