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Allele : Thra<tm1.1Fcas> thyroid hormone receptor alpha; targeted mutation 1.1, Francois Casas

Primary Identifier  MGI:5304668 Allele Type  Targeted
Attribute String  Null/knockout Gene  Thra
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was replaced with one in which a nucleotide substitution produced the amino acid substitution of leucine for methionine at position 109 (M109L). The floxed neo cassette inserted downstream of exon 4 was removed by cre-mediated recombination. Western blot analysis on quadriceps muscle extracts confirmed the absence of protein expression.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • p43<->,
  • p43<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

11 Publication categories