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Allele : Igk-J<tm1.1Lave> immunoglobulin kappa chain, joining region; targeted mutation 1.1, Laurent Verkoczy
Primary Identifier  MGI:5305129 Allele Type  Targeted
Gene  Igk-J Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The J1, J2, and J3 regions were replaced with a rearranged human light chain sequence of the HIV-1 broadly neutralizing antibody (bnAb) 2F5 and a floxed neo cassette. Cre-mediated recombination removed the neo cassette.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • 2F5 VL<+>,
  • 2F5,
  • 2F5 VL<+>,
  • 2F5
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories





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