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Allele : Tg(ED-L2-IL1RN/IL1B)#Tcw transgene insertion, Timothy C Wang
Primary Identifier  MGI:5308012 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(ED-L2-IL1RN/IL1B)#Tcw
Strain of Origin  C57BL/6 x SJL Is Recombinase  false
Is Wild Type  false
molecularNote  The Epstein-Barr virus ED-L2 promoter drives expression of a modified human IL1B cDNA. The modified human IL1B cDNA consists of the IL1RN signal sequence and a cDNA encoding for the 17 kDa mature human IL1B. Two lines were generated one with high expression and one with low expression.
  • mutations:
  • Insertion
  • synonyms:
  • L2-IL-1Beta,
  • L2-IL-1Beta
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1 Feature

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Genome

2 Expresses

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Carried By

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1 Driven By

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