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Allele : Brca1<tm1.1Jjon> breast cancer 1, early onset; targeted mutation 1.1, Jos Jonkers
Primary Identifier  MGI:5307254 Allele Type  Targeted
Attribute String  Humanized sequence, Hypomorph Gene  Brca1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette was inserted upstream of exon 5 and a T to G mutation, resulting in a cysteine to glycine substitution at amino acid position 61 (C61G) in a conserved RING domain, was introduced via homologous recombination. Cre mediated recombination removed the neo cassette.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Brca1<C61G>,
  • Brca1<C61G>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





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