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Allele : Cd8a<tm2.1(Cd4)Asin> CD8 subunit alpha; targeted mutation 2.1, Alfred Singer

Primary Identifier	MGI:5309010	Allele Type	Targeted
Attribute String	Inserted expressed sequence, Null/knockout	Gene	Cd8a
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 1-4 were replaced with a Cd4 cDNA and a floxed neomycin selection cassette. The selection cassette was subsequently removed by cre excision.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Cd8a<CD4>,
4in8,
Cd8a<CD4>,
4in8

earliestPublication:
Adoro S, et al. (2011) Coreceptor gene imprinting governs thymocyte lineage fate. EMBO J 31(2):366-77

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

5 Publication categories

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