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Allele : Lair1<tm1.1Jco> leukocyte-associated Ig-like receptor 1; targeted mutation 1.1, John E Coligan

Primary Identifier  MGI:5308465 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lair1
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 4 followed by a frt-flanked neomycin resistance (neo) cassette and a second loxP site inserted downstream of exon 8 via homologous recombination. Cre-mediated recombination removed exons 4-8 and the neo cassette. Flow cytometric analysis confirmed that LAIR1 could not be detected on T, B, and NK cells derived from splenocytes.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele