Primary Identifier | MGI:5308465 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lair1 |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 4 followed by a frt-flanked neomycin resistance (neo) cassette and a second loxP site inserted downstream of exon 8 via homologous recombination. Cre-mediated recombination removed exons 4-8 and the neo cassette. Flow cytometric analysis confirmed that LAIR1 could not be detected on T, B, and NK cells derived from splenocytes. |