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Allele : Ctnnb1<tm3Kba> catenin beta 1; targeted mutation 3, Konrad Basler

Primary Identifier  MGI:5308947 Allele Type  Targeted
Attribute String  Not Specified Gene  Ctnnb1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A point mutation was introduced into exon 4 resulting in a D164A mutation and a floxed hygromycin cassette was inserted via homologous recombination. In a second recombination event, a premature stop codon followed by a frameshift mutation were introduced at amino acid position 673 in exon 13 and this exon was fused to exon 15.
  • mutations:
  • Single point mutation,
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ctnnb1<dm>,
  • Beta-catenin<dm>,
  • Ctnnb1<dm>,
  • Beta-catenin<D164A-deltaC>,
  • Beta-catenin<dm>,
  • Beta-catenin<D164A-deltaC>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

17 Publication categories