| Primary Identifier | MGI:5308745 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mcph1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neo cassette was inserted upstream of exon 4. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 5. Cre-mediated recombination removed exons 4 and 5 as well as the neo cassette. Western blot analysis confirmed the absence of protein expression in primary mouse embryonic fibroblasts and the brain. |
