|  Help  |  About  |  Contact Us

Allele : Cigs2<tm1.1Anse> conserved intergenic sequence 2; targeted mutation 1.1, K Mark Ansel
Primary Identifier  MGI:5313809 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout Gene  Cigs2
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene cassette replaced the 810 bp encompassing the DNaseI hypersensitivity site 5 (HS5) in conserved non-coding sequence 2 (CNS-2) downstream of Il4, between it and Kif3a. Cre-mediated recombination removed the neo cassette. RT-PCR confirmed the reduction of Il4 and Il13 transcript expression in Th2 polarized CD4+ T cells.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • HS V<->,
  • deltaV,
  • HS V<->,
  • deltaV
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom