Primary Identifier | MGI:5312902 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Mirc33 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 1.7 kb region including the full coding sequence for both miroRNAs (Mir29a and Mir29b-1) was replaced with a hygromycin cassette via homologous recombination. In situ hybridization confirmed the absence of mir29a expression in the thymus of homozygous mice. |