Primary Identifier | MGI:5312914 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Vwf |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A guanine to adenine change in exon 28 caused an arginine to histidine change (R1325H), giving rise to a phenotype similar to that found in VWF-deficient mice. In addition, a floxed neomycin selection cassette was inserted in intron 28. This selection cassette was subsequently removed by cre mediated excision. |