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Allele : Vwf<tm1.1Diac> Von Willebrand factor; targeted mutation 1.1, Thomas G Diacovo

Primary Identifier  MGI:5312914 Allele Type  Targeted
Attribute String  Not Specified Gene  Vwf
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A guanine to adenine change in exon 28 caused an arginine to histidine change (R1325H), giving rise to a phenotype similar to that found in VWF-deficient mice. In addition, a floxed neomycin selection cassette was inserted in intron 28. This selection cassette was subsequently removed by cre mediated excision.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • VWF<R1326H>,
  • VWF<R1326H>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories