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Allele : Tg(Hnf1a-RB1*)XMiu transgene insertion X, Naoyuki Miura
Primary Identifier  MGI:5312916 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Hnf1a-RB1*)XMiu
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The rat Hnf1a enhancer/promoter drives expression of a phosphorylation-resistant mutant human RB1 cDNA. Phosphorylation resistance was created by mutating 12 of 16 consensus phosphorylation sites (8 serines and 4 threonines) to alanines. High levels of transgene expression are detected in the livers of mice in this line.
  • mutations:
  • Insertion
  • synonyms:
  • mt-Rb,
  • TGX,
  • TGX,
  • mt-Rb
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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