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Allele : Bcl2<tm1.1Sjk> B cell leukemia/lymphoma 2; targeted mutation 1.1, Stanley Korsmeyer

Primary Identifier  MGI:5313428 Allele Type  Targeted
Gene  Bcl2 Transmission  Germline
Strain of Origin  129X1/SvJ Is Recombinase  false
Is Wild Type  false
molecularNote  Nucleotide substitutions in exon 2 were used to replace the threonine at 69 and serines at positions 70 and 84 with alanines (T69A, S70A and S84A). Flp-mediated recombination removes the puro cassette inserted downstream of the modified exon 2.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Bcl2<AAA>,
  • Bcl2<AAA>,
  • Bcl2<tm1.1Blev>,
  • Bcl2<tm1.1Blev>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

11 Publication categories