Primary Identifier | MGI:5313428 | Allele Type | Targeted |
Gene | Bcl2 | Transmission | Germline |
Strain of Origin | 129X1/SvJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Nucleotide substitutions in exon 2 were used to replace the threonine at 69 and serines at positions 70 and 84 with alanines (T69A, S70A and S84A). Flp-mediated recombination removes the puro cassette inserted downstream of the modified exon 2. |