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Allele : b2b251Clo Mutant line 251; Bench to Bassinet Program (B2B/CVDC), mutation 251 Cecilia Lo
Primary Identifier  MGI:5313696 Allele Type  Chemically induced (ENU)
Gene  b2b251Clo Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  B2B/CvDC
description  Summative Diagnosis:
Cardiovascular defect: Double outlet right ventricle (DORV), overriding aorta, perimembranous and muscular ventricular septal defects (VSD), and one mutant with hypoplastic transverse arch.
Non-cardiovascular phenotype: Cystic lungs.

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID Code Description
1220 Tubular hypoplasia of aorta + coarctation
1310 Ventricular septal defect, membranous
1320 Ventricular septal defect, muscular
1340 Ventricular septal defect, ECD type
3810 Heart disease
4200 Respiratory anomaly

molecularNote  This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

3 Publication categories





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