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Allele : Src<tm1Mul> Rous sarcoma oncogene; targeted mutation 1, William J Muller

Primary Identifier	MGI:5314758	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Src
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 4. An FRT-flanked neo, IRES, and GFP cassette with a 3' loxP site downstream of exon 6. Flp-mediated recombination removed the neo, IRES and GFP cassette.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
c-Src<L>,
c-Src<L>

earliestPublication:
Marcotte R, et al. (2012) Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis. Proc Natl Acad Sci U S A 109(8):2808-13

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

9 Publication categories

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