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Allele : Cdo1<tm1.1Mhst> cysteine dioxygenase 1, cytosolic; targeted mutation 1.1, Martha H Stipanuk

Primary Identifier	MGI:5315594	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Cdo1
Transmission	Germline	Strain of Origin	C57BL/6
Is Recombinase	false	Is Wild Type	false

molecularNote

One loxP site was inserted upstream of exon 3 while an FRT flanked neo cassette followed by a second loxP site was inserted downstream. Properly targeted homozygous mice were bred to cre-deleter mice to excise exon 3 and the neo selection cassette.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Ueki I, et al. (2011) Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide. Am J Physiol Endocrinol Metab 301(4):E668-84

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

6 Publication categories

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