Primary Identifier | MGI:5315747 | Allele Type | Chemically induced (ENU) |
Attribute String | Hypomorph | Gene | Wdr19 |
Inheritance Mode | Recessive | Strain of Origin | FVB/NJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Mice carrying Tg(Hba1-Gfp)1Ew were treated with ENU. A T to C transition was identified at position 2249 in exon 19 causing a leucine-to-proline substitution at amino acid position 750. Immunofluorescence analysis detected protein expression in mutant MEFs. This is a hypomorphic allele. |