| Primary Identifier | MGI:5316034 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Tesc |
| Transmission | Germline | Strain of Origin | (C57BL/6NTac x 129S6/SvEvTac)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 4, 5, and 6 were replaced by a neomycin resistance gene in reverse orientation. RT-PCR confirmed the absence of normal transcript. A low level of truncsted transcript lacking exon 3 in addition to exons 4, 5, and 6 was detected. Western blot analysis confirmed the absence of protein in brain, heart, and platelets. |
