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Allele : Yap1<tm2.1Fcam> yes-associated protein 1; targeted mutation 2.1, Fernando D Camargo

Primary Identifier  MGI:5316452 Allele Type  Targeted
Gene  Yap1 Transmission  Germline
Strain of Origin  (C57BL/6 x 129S4/SvJae)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Nucleotide substitutions (TCC to GCG) results in the amino acid substitution of alanine for serine at position 79 (S79A). Flp-mediated recombination removed the FRT-flanked neo cassette used for selection. This mutation is predicted to disrupt protein interaction with TEAD proteins but not other DNA-binding co-factors.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Yap1<S79A>,
  • Yap1<S79A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories