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Allele : Gjc1<tm1.2(Gjd2)Kwi> gap junction protein, gamma 1; targeted mutation 1.2, Klaus Willecke

Primary Identifier	MGI:5317163	Allele Type	Targeted
Attribute String	Inserted expressed sequence, Null/knockout	Gene	Gjc1
Transmission	Germline	Strain of Origin	129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase	false	Is Wild Type	false

molecularNote

Cre-mediated recombination of Gjc1^{tm1.1(Gjd2)Kwi} removed exon 3 and allowed for expression of the mouse Gjd2 cDNA. Western blot analysis confirmed the expression of Gjd2 in the retina.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Cx45<Cx36>,
Cx45<Cx36>

earliestPublication:
Frank M, et al. (2010) Neuronal connexin-36 can functionally replace connexin-45 in mouse retina but not in the developing heart. J Cell Sci 123(Pt 20):3605-15

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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