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Allele : Stab2<tm1Ami> stabilin 2; targeted mutation 1, Atsushi Miyajima

Primary Identifier	MGI:5318244	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Stab2
Transmission	Germline	Strain of Origin	(C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase	false	Is Wild Type	false

molecularNote

Genomic sequence including most of exon 1 and part of intron 1 was replaced with a lacZ and neo expressing cassette via homologous recombination. RT-PCR and immunostaining confirmed the absence of expression in homozygous mice.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Hirose Y, et al. (2012) Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis. Proc Natl Acad Sci U S A 109(11):4263-8

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

6 Publication categories

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