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Allele : Tg(CMV-IGL@AL080)55Dcs transgene insertion 55, David C Seldin

Primary Identifier  MGI:5318684 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CMV-IGL@AL080)55Dcs
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene expresses the human amyloidogenic immunoglobulin lambda 6 light chain and the bovine growth hormone polyadenylation sequence under the control of the cytomegalovirus (CMV) promoter. The lambda 6 light chain cDNA was generated by reverse transcription from RNA prepared from bone marrow collected from patient AL080 (GenBank sequence no. EF589388) who had rapidly progressive multiorgan amyloid light chain amyloidosis.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(CMV-IGL6-AL080)55Dcs,
  • Tg(CMV-IGL6-AL080)55Dcs
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories