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Allele : Pax6<tm1.1Xzh> paired box 6; targeted mutation 1.1, Xin Zhang
Primary Identifier  MGI:5317866 Allele Type  Targeted
Attribute String  Conditional ready, Modified regulatory region, No functional change Gene  Pax6
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site and an Sph I site were inserted upstream of the distal enhancer element and the 450 bp proximal enhancer element was replaced with an FRT flanked neo cassette and a loxP site. Flp-mediated recombination removed the neo cassette. RT-PCR analysis indicates reduced pancreatic expression in homozygous mice at E15.5.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Pax6<deltaPE>,
  • Pax6<deltaPE>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





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