| Primary Identifier | MGI:5318539 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Slc12a6 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An FRT and LoxP flanked neo cassette was inserted upstream of exon 18 and a loxP site was inserted downstream of exon 18 via homologous recombination. Cre mediated recombination removed exon 18. RT-PCR analysis detected the presence of a lower molecular weight product. Western blot analysis detected a small amount of truncated protein in brain lysates from homozygous mice. |