| Primary Identifier | MGI:5423982 | Allele Type | Spontaneous |
| Gene | Lmx1a | Inheritance Mode | Recessive |
| Strain of Origin | 129S5/SvEvBrd | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The mutation is an intergenic deletion spanning approximately 13.48 Kb of the gene (7.89 Kb upstream and 5.36 Kb downstream of exon 3, inclusive). The mutation is predicted to cause a frameshift in the translation of the encoded protein resulting in truncation after 91 amino acids. QRT-PCR confirmed reduced transcript expression at E10.5. |
