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Allele : Gnas<tm1.1Plag> GNAS complex locus; targeted mutation 1.1, Antonius Plagge
Primary Identifier  MGI:5320896 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Gnas
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Exon A20 was replaced with a gene trap vector containing (5' to 3'): lox2272 site, loxP site, FRT site, lacZ gene, and cDNA encoding exon 2SA. Flp-mediated recombination removed the neo cassette. qRT-PCR confirmed a 90% downregulation of transcript expression.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • XLlacZGT,
  • Gnasxl<tm2Pla>,
  • Gnasxl<tm2Pla>,
  • XLlacZGT
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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