Primary Identifier | MGI:5320447 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Hoxb3 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP-flanked neomycin resistance cassette (neo) was inserted 3' of the coding sequence of Hoxb3 and was subsequently deleted by transient Cre recombinase mediated recombination in the targeted ES cells, leaving a single loxP site downstream of Hoxb3. Presence of the loxP site does not affect expression of the gene. |