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Allele : Hk2<tm1.1Uku> hexokinase 2; targeted mutation 1.1, University of Kuopio

Primary Identifier  MGI:5320615 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Hk2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP-flanked neomycin resistance (neo) cassette was inserted into intron 3 and a third loxP site into intron 10. The neo cassette was deleted by Cre recombinase in vivo, leaving a single loxP site in intron 3. Crossing mice with this allele to animals expressing Cre recombinase will result in deletion of exons 4-10, inactivating the gene, in the offpring in the tissues or cell types where Cre is expressed.
  • mutations:
  • Insertion
  • synonyms:
  • Neoless Oy1109B,
  • Hk2lox,
  • Neoless Oy1109B,
  • neoless Hk2lox,
  • neoless Hk2lox,
  • Hk2lox
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

14 Publication categories