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Allele : Frzb<tm1.1Fplu> frizzled-related protein; targeted mutation 1.1, Frank P Luyten
Primary Identifier  MGI:5320664 Allele Type  Targeted
Attribute String  Null/knockout Gene  Frzb
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1 was floxed and an FRT flanked neo cassette was inserted downstream of exon 1 via homologous recombination. Cre mediated recombination deleted exon 1 leaving the neo cassette insertion intact. RT-PCR and immunohistochemical analyses confirmed the absence of mRNA and protein expression in cartilage from homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

8 Publication categories





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