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Allele : Car5a<tm1Sly> carbonic anhydrase 5a, mitochondrial; targeted mutation 1, William S Sly

Primary Identifier  MGI:5425618 Allele Type  Targeted
Attribute String  Null/knockout Gene  Car5a
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  All of exon 3 as well as 150 bp of intron 2 and 3.05 kb of intron 3 were replaced by a PGK-neomycin resistance gene. This removed two of the three zinc binding histidine residues and created a frameshift beginning in exon 4. No protein was detected by Western blot analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories