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Allele : Tmc2<tm1.1Ajg> transmembrane channel-like gene family 2; targeted mutation 1.1, Andrew J Griffith
Primary Identifier  MGI:5427099 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Tmc2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 7 was replaced with an IRES-lacZ cassette and a floxed pgk-neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. At P28 beta-galactosidase activity is detected in hair cells of the cristae ampullaris and very faintly in in hair cells of the saccular and utricular maculae.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Tmc2<delta>,
  • Tmc2<delta>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

21 Publication categories





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