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Allele : Apoe<tm2(APOE_i3)Yhg> apolipoprotein E; targeted mutation 2, Yadong Huang

Primary Identifier  MGI:5427462 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence Gene  Apoe
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  The coding sequence (exons 2 through 4) was replaced with the corresponding human genomic sequence encoding isoform 3. A loxP site was inserted 5' of the human sequence and a neo cassette with a 5' loxP site was inserted downstream of the human sequence.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • E3<+>,
  • ApoE3-fKI,
  • ApoE3-fKI,
  • E3<+>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories