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Allele : Fcgr2b<tm1.2Jsv> Fc receptor, IgG, low affinity IIb; targeted mutation 1.2, J Sjef Verbeek

Primary Identifier	MGI:5427927	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Fcgr2b
Transmission	Germline	Strain of Origin	B6.Cg-Thy1<a>
Is Recombinase	false	Is Wild Type	false

molecularNote

Cre-mediated recombination removed the neo cassette and exons 4 and 5. Flow cytometry confirmed the near absence of protein expression in B cells.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
FcgRIIBB6<->,
FcgRIIBB6<->,
Fcgr2b<tm1.2Sjv>,
Fcgr2b<tm1.2Sjv>

earliestPublication:
Boross P, et al. (2011) The inhibiting Fc receptor for IgG, FcgammaRIIB, is a modifier of autoimmune susceptibility. J Immunol 187(3):1304-13

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

13 Publication categories

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