Primary Identifier | MGI:5428890 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Sox17 |
Transmission | Germline | Strain of Origin | (C57BL/6J x 129S6/SvEvTac)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The translational stop codon in exon 5 was replaced with an in-frame open reading frame of mCherry followed by a floxed PGK-neo cassette. Cre mediated recombination removed the neo cassette. Expression and localization of the fusion protein recapitulates endogenous gene expression and localization. |