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Allele : Tg(SNCA)ARyot transgene insertion A, Ryosuke Takahashi

Primary Identifier	MGI:5429214	Allele Type	Transgenic
Attribute String	Humanized sequence, Inserted expressed sequence	Gene	Tg(SNCA)ARyot
Strain of Origin	C57BL/6J	Is Recombinase	false
Is Wild Type	false

molecularNote

The transgene consists of the PAC AF163864 and BAC AC097478 and contains 28 kb fo the 5' and 50 kb of the 3' flanking sequences in addition to the entire human gene. Lines A and B (8 and 1 copy, respectively) were generated.

mutations:
Insertion

synonyms:
alpha-syn BAC tg,
alpha-syn BAC tg

earliestPublication:
Yamakado H, et al. (2012) alpha-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion. Neurosci Res 73(2):173-7

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

10 Publication categories

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