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Allele : Tg(Camk2a-tTA)2Stl transgene insertion 2, Susumu Tonegawa

Primary Identifier	MGI:5432122	Allele Type	Transgenic
Attribute String	Transactivator	Gene	Tg(Camk2a-tTA)2Stl
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

The transgene construct contained the tetracycline transactivator (tTA) coding sequence downstream of a loxP-STOP-loxP fragement. This was inserted downstream of the alpha-CamKII (Camk2a) promoter in the final construct. A founder linse 1 and 2 were established.

mutations:
Insertion

synonyms:
Tg2 line2,
Tg2 line2

earliestPublication:
Nakashiba T, et al. (2008) Transgenic inhibition of synaptic transmission reveals role of CA3 output in hippocampal learning. Science 319(5867):1260-4

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

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