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Allele : Ctnnb1<tm1.1Wvv> catenin beta 1; targeted mutation 1.1, Wendy van Veelen

Primary Identifier  MGI:5430597 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Ctnnb1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 12 and a floxed FRT flanked PGK-neomycin selection cassette was inserted downstream of exon 15 followed by a duplication of exons 12-15. A tyrosine to glutamic acid codon change was incorporated at codon 654 of the duplicated exon 13. Correctly targeted mice were bred to "CAG-flp" mice to remove the selection cassette.
  • mutations:
  • Insertion
  • synonyms:
  • beta-catenin<Y654E-fl>,
  • beta-catenin<Y654E-fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories