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Allele : Clcn7<tm1.1Lex> chloride channel, voltage-sensitive 7; targeted mutation 1.1, Lexicon Genetics

Primary Identifier  MGI:5431240 Allele Type  Targeted
Attribute String  Hypomorph Gene  Clcn7
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
Project Collection  Lexicon
molecularNote  A loxP site was inserted upstream of exon 1. A neo cassette with a 3' loxP site was inserted downstream of exon 1. Cre mediated recombination removed the neo cassette. QRT-PCR confirmed the absence of the standard transcript in the liver, heart, lung, kidney, muscle, brain and bone (with or without marrow) and the absence of the alternative transcript in the liver, heart, lung, kidney, muscle and brain but not bone (with or without marrow).
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories