Primary Identifier | MGI:5432141 | Allele Type | Targeted |
Gene | Trp53 | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Nucleotide substitution (TCT-to-GCG) result in the amino acid substitution of serine with alanine at position 312 (p.S312A). A loxP site flanked neomycin resistance gene cassette that was inserted was removed by Cre-mediated recombination. |