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Allele : Tg(tetO-IGF1R)1Ramo transgene insertion 1, Roger A Moorehead

Primary Identifier  MGI:5432255 Allele Type  Transgenic
Attribute String  Humanized sequence, Inducible, Inserted expressed sequence Gene  Tg(tetO-IGF1R)1Ramo
Strain of Origin  FVB Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The tetracycline response element (TRE or tetO) was used to drive inducible expression of the full-length human IGF1R. In double transgenic mice also expressing the tetracycline transactivating or reverse transactivating element (tTA or rtTA), expression of IGF1R can be regulated by doxycycline administration or removal. Four lines were created.
  • mutations:
  • Insertion
  • synonyms:
  • TRE-IGF1R1,
  • TRE-IGF1R1
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories