| Primary Identifier | MGI:5433215 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(Crx-Atoh7,-cre)251Gla |
| Strain of Origin | (C57BL/6J x SJL/J)F2 or (B6;129-Gt(ROSA)26Sor<tm1Sho>/J x (C57BL/6 x SJL)F1) | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | The Atoh7 (Math5) and cre recombinase cDNAs, separated by an internal ribosomal entry site (IRES) and followed by an SV40 polyadenylation sequence, were cloned into a plasmid upstream of a 2.4 kb fragment of the mouse Crx gene that contained the promoter and proximal regulatory region. The linearized purified transgene was injected into fertilized oocytes. 2 founders and 2 lines were obtained, crossed to GFP reporter mice and analyzed for GFP and cre expression. A representative line, 251, was chosen for further analysis. |
