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Allele : Ptpn2<tm2.1Ttig> protein tyrosine phosphatase, non-receptor type 2; targeted mutation 2.1, Tony Tiganis

Primary Identifier  MGI:5436249 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptpn2
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 2 and an FRT flanked pgk-neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Cre mediated recombination removed exon 2 and the pgk-neo cassette. Western blot analysis confirmed the absence of full length protein in tissues from homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ptpn2<ex2->,
  • Ptpn2<ex2->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele