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Allele : Pink1<tm1.1Wrst> PTEN induced putative kinase 1; targeted mutation 1.1, Wolfgang Wurst
Primary Identifier  MGI:5436308 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pink1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site and FRt flanked neo cassette were inserted upstream of exon 2 and a loxP site was inserted downstream of exon 3 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exons 2 and 3. RT-PCR analysis indicates a dramatic reduction in mRNA expression in homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Pink1<->,
  • Pink1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories





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