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Allele : Eif2ak2<tm1Ajs> eukaryotic translation initiation factor 2-alpha kinase 2; targeted mutation 1, Anthony J Sadler
Primary Identifier  MGI:5438001 Allele Type  Targeted
Gene  Eif2ak2 Transmission  Germline
Strain of Origin  129 Is Recombinase  false
Is Wild Type  false
molecularNote  Nculeotide substitutions (AAG to CGG) result in the amino acid substitution of arginine for lysine at position 271 (K271R). Cre-mediated recombination removed the neo cassette and leaves a 121 lox in intron 9. This mutation is expected to ablate kinase activity.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • eIF2k2<tm1Lri>,
  • eIF2k2<tm1Lri>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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7 Publication categories





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