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Allele : Mapt<tm1.1Cole> microtubule-associated protein tau; targeted mutation 1.1, Michael Coleman
Primary Identifier  MGI:5440079 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Mapt
Transmission  Germline Strain of Origin  C57BL/6JOlaHsd
Is Recombinase  false Is Wild Type  false
description  ES cells = TMDB10 (C57BL/6JOlaHsd)
molecularNote  Exon 10 was replaced with a floxed neo cassette and a modified exon 10 in which a C to T transition results in the amino acid substitution of leucine for proline at position 301 (P301L). Cre-mediated recombination removed the neo cassette.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • tau<P301L>,
  • tau<P301L>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories





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